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KMID : 0378019730160010080
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New Medical Journal
1973 Volume.16 No. 1 p.80 ~ p.84
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Sensitivity Patterns of the Ps. Aeruginosa to Antibiotics and Disinfectants Isolated from Chrontic Wounds
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Abstract
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In general, the pseudomonas strains have been resistant to various antibiotics and disinfectants. In recent years, the infection rate of these organism has been reported increasingly associated with chronic wounds.
In this report, author has isolated the 47 strains of pseudomonas aeruginosa from chronic wounds associated with orthopedic surgical field at Taegu military Hospital in 1972 and studied the various antibacterial sensitivity patterns against pseudomonas strains to search she responsible antibiotics and disinfectants to them.
The results were obtained as follows;
1) In antibiotic sensitivity of isolated strains tested by plate dilution method, most of all strians were resistant to Kanamycin and Neomycin, but a few strains were moderate sensitive to Colistin, Polymyxin B and Terramycin.
2) All the strains tested in term of antibacterial sensitivity to disinfectants were sensitive to mer￢thiolate, mercury bichloride(0.01%), H202(3.0%), lactic acid(1.0%) and saturated boric acid with alcohol within one minute.
3) With the minimum bacteriocidal concentration of usual disinfectants, merthiolate was found to be most sensitive and Ila02, Iodine, Lactic Acid and others in the order of sensitivity.
4) In combined effects with disinfectants and antibiotics, no definite conclusion could be reached due to paucity of tested strains and brevity of tested method except Hygiene seemed to be very stable in various antibiotics, and in combined effects with 2 kinds of disinfectants depend on the kinds of disinfectants.
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KEYWORD
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